000			03237 a2200265 4500
008			1969
020			_aS/N
040			_aGAMADERO _bINGLES _cGAMADERO
041			_aeng
050	0	0	_aRS190 _bP55 _c1969
100			_aGEARIEN JAMES E.
245			_aMETHODS OF DRUG ANALUSIS
250			_a1era. edición
260			_bGEARIEN GRABOWWSKI _aCHICAGO _c1969
300			_a281pg _bILUSTRADO _c15 cm x24 cm
505			_a.FUNCTIONAL GROUP METHODS .PHYSICOCHEMICAL METHODS
520			_aChemical compounds are usually analyzed through reactions that are specific for an ion, radical, or functional group. In inorganic analysis by volumetric means it has become common to classify these reactions according to the type of reaction occurring during the titration procedure. For example, such terms as acidimetry, alkalimetry, precipitation, or oxidation-reduction are commonly employed to classify such titrations. In organic analysis such a classification is less meaningful. In such analyses it is more useful to consider the functional group involved in the reaction. Since most analytical reactions are not specific for a single compound but may be employed in analyzing any compound containing a like ion, radical, or functional group, this lack of specificity permits a broad means of classifying analytical methods. It further permits a classification that may be employed to select methods of analysis for new or previously unanalyzed compounds. While such classification is of great value to students of pharmaceutical analysis, it must be understood that no single determination can always be used for the analysis of a specific functional group, ion, or radical. The presence of other groups, either in the compound being analyzed or in other compounds present in a pharmaceutical preparation, may interfere with, or prevent, the reaction from being quantitative. For this reason a number of analytical reactions have been developed for each functional group. In addition to knowing the various reactions applicable to each functional group, the analyst must understand thoroughly their limitations so as to select that reaction most suitable for the mixture or compound being analyzed. For example, an analyst must not only recognize that phenols may be determined by measuring the quantity of bromine employed to convert the phenol to 2,4,6-tribromophenol but must also realize that this reaction will be worthless to analyze phenol dissolved in a vegetable oil. Such an oil, because of its unsaturation, will also react with bromine and interfere with its determination. The analyst therefore must be familiar with the analytical reactions and methods available for quantitative determinations and must be able to select the best reaction and utilize it in the proper analytical procedure for the compound being analyzed. He cannot rely solely upon standard procedures but must be able to modify these to develop suitable assays for new compounds and new pharmaceutical mixtures.
526			_aIngeniería Ambiental
650		0	_aingeniería ambiental _91756
942			_cLIB _2ddc _e1ra.edición
945			_a1 _badmin _c1260 _dNorma Gabriela Corona Arreguin
999			_c6701 _d6701